Affiliation:
1. Universidade de São Paulo, Brazil
Abstract
Abstract When seeking orthodontic treatment, many adolescents and adult patients present with deciduous teeth. Naturally, deciduous teeth will inevitably undergo exfoliation at the expected time or at a later time. Apoptosis is the biological trigger of root resorption. In adult patients, deciduous teeth should not be preserved, as they promote: infraocclusion, traumatic occlusion, occlusal trauma, diastemata and size as well as morphology discrepancy malocclusion. Orthodontic movement speeds root resorption up, and so do restoring or recontouring deciduous teeth in order to establish esthetics and function. Deciduous teeth cells are dying as a result of apoptosis, and their regeneration potential, which allows them to act as stem cells, is limited. On the contrary, adult teeth cells have a greater proliferative potential. All kinds of stem cell therapies are laboratory investigative non authorized trials.
Subject
Oral Surgery,Orthodontics
Reference7 articles.
1. Feeder-free derivation of induced pluripotent stem cells from human immature dental pulp stem cells;Beltrão-Braga PC;Cell Transplant,2011
2. Reabsorções dentárias nas especialidades clínicas;Consolaro A,2012
3. Apoptose na odontogênese: durante a fragmentação da lâmina dentária e da bainha epitelial de Hertwig e no epitélio reduzido o órgão do esmalte. Estudo imunocitoquímico em camundongos;Lourenço SQC,1997
4. Reabsorção dentária fisiológica: estudo dos mecanismos (apoptose) e das moléculas desencadeadoras (Bmp-4 e Gelatinase B) em dentes decíduos de gatos;Lourenço SQC,1999
5. Induction of pluripotent stem cells from human third molar mesenchymal stromal cells.;Oda Y;J Biol Chem.,2010
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