Affiliation:
1. Universidade Federal Rural de Pernambuco, Brazil
2. Empresa de Assistência Técnica e Extensão Rural da Paraíba, Brazil
Abstract
ABSTRACT: The aim of this work was to describe the epidemiological, clinical and pathological aspects of two outbreaks of spontaneous poisoning caused by Froelichia humboldtiana in cattle in Pernambuco, northeastern Brazil and reproduce experimentally this poisoning in cattle. Spontaneous poisonings of primary photosensitization occurred in two farms at the municipalities of Cachoeirinha and São Caetano and affected twenty-two adult bovines and two suckling calves after the rainy season. All bovines have recovered 21 days after they were removed from the pasture. To reproduce experimental poisoning, three cows and a calf were maintained in a pasture with 1ha composed by F. humboldtiana during 14 days. Clinical signs and skin lesions were similar in both spontaneous and experimental poisoning and consisted of cutaneous itching and hyperemia of non-pigmented areas of skin that evolved into edema, exudative dermatitis and extensive areas of skin necrosis. Serum levels of aspartate aminotransferase (AST), gamma glutamyltransferase (GGT), total, direct and indirect bilirubin were normal in all cattle examined. Histologically, lesions consisted of epidermal necrosis, hyperkeratosis with large amounts of degenerate neutrophils and acanthosis. In the dermis, edema and inflammatory infiltrate composed of eosinophils, lymphocytes and plasma cells mainly around the blood vessels were observed. In the experimental group, clinical signs of photosensitization were observed after the third day of F. humboldtiana consumption. The suckling calf displayed mild clinical signs of photodermatitis on the 8th day of the experiment. It was estimated that the average consumption of F. humboldtiana necessary to initiate clinical signs in each adult bovine was 78kg.
Reference19 articles.
1. Surtos de fotossensibilização e dermatite alérgica em ruminantes e equídeos no Nordeste do Brasil;Amado G.P.;Pesq. Vet. Bras.,2018
2. Primary photosensitization and contact dermatitis caused by Malachra fasciata Jacq. N.V. (Malvaceae) in sheep;Araújo V.O.;Toxicon,2017
3. Milk transfer of pyrrolizidine alkaloids in cattle;Dickinson J.O.;J. Am. Vet. Med. Assoc.,1976
4. Botanal: a comprehensive sampling and computing procedure for estimating pasture yield and composition. II. Computational package.;Hargreaves J.N.G.,1981
5. Plant Associated Toxins;James L.F.,1994
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献