Affiliation:
1. Pontifícia Universidade Católica do Paraná, Brazil
Abstract
ABSTRACT: Allergic dogs are commonly sensitized to food allergens. We evaluated the use of the prick test to diagnose food allergies in dogs with pruritus and the efficacy of an exclusion diet based on the test. The prick test was performed in 10 healthy dogs and 34 dogs with pruritus, of which 25 received an exclusion diet for 60 days and was challenged with positive food on the test. pVAS and CADESI-4 were assessed on days 0, 30, and 60 after re-exposure. As a result, two control group dogs reacted to a single food allergen, milk and wheat. Of the 25 dogs with pruritus that reacted to food allergens, 24 (96%) reacted to more than one food allergen, and only one (4%) reacted to a single food protein: pork. In the test group (n=25), there was a significant improvement of pVAS and CADESI-4 after 30 and 60 days of dietary exclusion, with significant worsening of the scores with food allergen challenge. In conclusion, the prick test can be used for screening food allergens to make an exclusion diet.
Reference32 articles.
1. Immunomodulatory in vitro effects of oclacitinib on canine T-cell proliferation and cytokine production;Banovic F.;Vet. Dermatol.,2019
2. Patch testing and allergen-specific serum IgE and IgG antibodies in the diagnosis of canine adverse food reactions;Bethlehem S.;Vet. Immunol. Immunopathol.,2012
3. Food allergy in canines: a review;Bhagat R.;J. Entomol. Zool. Stud.,2017
4. Food allergy in dogs and cats: current dermatological perspectives;Carlotti D.-N.;Eur. Coll. Vet. Dermatol.,2011
5. Molecular and cellular mechanisms of food allergy and food tolerance;Chinthrajah R.S.;J. Allergy Clin. Immunol.,2016