Pregnancy and multiple sclerosis: the initial results from a Brazilian database-Reference-Cited by-同舟云学术

Pregnancy and multiple sclerosis: the initial results from a Brazilian database

Published:2009-09 Issue:3a Volume:67 Page:657-660
ISSN:0004-282X
Container-title:Arquivos de Neuro-Psiquiatria
language:
Short-container-title:Arq. Neuro-Psiquiatr.

Author:

Fragoso Yara Dadalti¹,Finkelsztejn Alessandro²,Comini-Frota Elizabeth Regina³,Gama Paulo Diniz da⁴,Grzesiuk Ansderson Kuntz⁵,Khouri Jussara Mathias Netto⁶,Alves-Leon Soniza Vieira⁷,Morales Rogério de Rizo⁸,Lana-Peixoto Marco Aurélio⁸,Rocha Cristiane Franklin da⁸

Affiliation:

1. Universidade Metropolitana de Santos, Brazil

2. Hospital de Clínicas de Porto Alegre, Brazil

3. Universidade Federal de Minas Gerais, Brazil

4. Pontifícia Universidade Católica de São Paulo, Brazil

5. Hospital Santa Rosa, Brazil

6. Universidade Católica do Paraná; Universidade Positivo, Brazil

7. Universidade Federal do Estado do Rio de Janeiro

8. Universidade Federal do Estado do Rio de Janeiro, Brazil

Abstract

PURPOSE: Pregnancy management poses an extra challenge to physicians and their multiple sclerosis (MS) patients. There are few papers reporting databases on the subject. METHOD: Brazilian database from nine MS clinical and research units, with complete data on 47 pregnant women (49 pregnancies). RESULTS: Despite relatively high exposure to MS medications, no birth defects were reported. Low birth weight and prematurity were similar to those for developing countries. Three complications may have been associated with these medications, while three others were considered to be of purely obstetric nature. CONCLUSION: Our results confirm previous findings on lower relapse rate during pregnancy and add to the present literature informing on data related to drug exposure.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Link

http://www.scielo.br/pdf/anp/v67n3a/v67n3aa15.pdf

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