Affiliation:
1. Federal University of Pernambuco, Brazil
Abstract
AIM: To evaluate the degree of influence that periportal fibrosis has on clinical development and the long term results of surgical treatment on patients with hepatic-splenic schistosomiasis with previous gastrointestinal hemorrhages. METHODS: During the period of 1992-1998, 111 patients underwent surgical treatment for the treatment of hepatic-splenic schistosomiasis with previous gastrointestinal hemorrhages. The degree of fibrosis was classified as: degree I - the portal spaces show a rich increase of young connective cells, a slight collagen production and a varying presence of inflammatory infiltrate. The periportal blade unchangeable (29/111); degree II - there is an expansion of the connective tissue with the emission of radial collagen septa, producing a star shaped aspect (38/111); degree III - the connective septa form bridges with other portal spaces or with the vein, with evident angiomatoid neo-formation (44/111). CONCLUSION: The patients with periportal fibrosis degree I present recurrent hemorrhages statistically less than patients with periportal fibrosis degrees II and III, and that the intensity of the periportal fibrosis is not the only pathophysiological factor of the esophageal varices, gastric varices, prevalence of post-operative portal vein thrombosis and hematological and biochemical alterations of the patients with pure mansoni schistosomiasis.
Reference33 articles.
1. Characteristic sonographic pattern of schistosomal hepatic fibrosis;Abdel-Wahab MF;Am J Trop Med Hyg,1989
2. Anastomose espleno-renal distal em esquistossomótico: revisão de 200 pacientes operados há 11 e 22 anos;Abrantes WL;Clin Bras Cir Col Bras Cir,1995
3. Morphology of chronic collagen resorption: A study on the late stages of schistosomal granuloma involution;Andrade ZA;Am J Pathol,1988
4. Hepatic connective tissue changes in hepatosplenic schistosomiasis;Andrade ZA;Hum Pathol,1992
Cited by
13 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献