Demonstration of antibody and cellular immune response to brain extract in West and Lennox-Gastaut syndromes-Reference-Cited by-同舟云学术

Demonstration of antibody and cellular immune response to brain extract in West and Lennox-Gastaut syndromes

Published:1984-06 Issue:2 Volume:42 Page:126-131
ISSN:0004-282X
Container-title:Arquivos de Neuro-Psiquiatria
language:
Short-container-title:Arq. Neuro-Psiquiatr.

Author:

Mota Norma G. S.¹,Rezkallah-Iwasso M. Thereza¹,Peraçoli M. Terezinha S.¹,Montelli Terezinha C. B.¹

Affiliation:

1. UNESP

Abstract

We investigated humoral and cellular immune response to brain tissues in 15 patients with West syndrome, in 9 patients with Lennox-Gastaut syndrome and in 20 healthy children. High levels of a precipitating antibody to a saline extract of brain tissue were detected in all patients; leucocyte migration inhibition test with the same antigen was found to be positive in most of them. The role of this autoimmune response in the pathogenesis of West and Lennox-Gastaut syndromes remains to the elucidated.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Link

http://www.scielo.br/pdf/anp/v42n2/04.pdf

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