Neuropathology of two Brazilian autopsied cases of tropical spastic paraparesis / HTLV-I associated myelopathy (TSP/HAM) of long evolution-Reference-Cited by-同舟云学术

Neuropathology of two Brazilian autopsied cases of tropical spastic paraparesis / HTLV-I associated myelopathy (TSP/HAM) of long evolution

Published:2002-09 Issue:3A Volume:60 Page:531-536
ISSN:0004-282X
Container-title:Arquivos de Neuro-Psiquiatria
language:
Short-container-title:Arq. Neuro-Psiquiatr.

Author:

Castro-Costa Carlos Maurício de¹,Dom René²,Carton Herwig²,Goubau Patrick³,Santos Terezinha de Jesus Teixeira¹,Ferreira Márcia Valéria Pitombeira⁴,Silva Neto Francisco Ursino da⁴

Affiliation:

1. Federal University of Ceará; Federal University of Ceará, Brazil

2. Katholieke Universiteit Leuven, Belgium

3. Université Catholique de Louvain, Belgium

4. Federal University of Ceará, Brazil

Abstract

We report on a neuropathological analysis of two cases of TSP/HAM originating from Brazil. These two cases had, respectively, an evolution of 13 and 40 years. The main neuropathological findings consisted of spinal cord atrophy, mainly the lower thoracic cord, diffuse degeneration of the white and grey matter, rare foci of mononuclear and perivascular cuffs, and hyaline hardening of arteriolae. The supraspinal structures were normal, excepting for a slight gliosis in the cerebellum. An analysis on the long evolutive cases as described in the literature is outlined in this study.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Link

http://www.scielo.br/pdf/anp/v60n3a/11120.pdf

Reference20 articles.

1. Necropsy findings in HTLV-I associated myelopathy;Akizuki S;Lancet,1987

2. HTLV-I and the nervous system;Akizuki S,1989

3. Pathological and immunological observations on tropical spastic paraparesis in patients from Jamaica;Picardo P;Ann Neurol,1988

4. An autopsy case of HTLV-I associated myelopathy (HAM);Furuzono H;Clin Neurol (Japan),1989

5. An autopsy case of HTLV-I associated myelopathy;Kobayashi I;Neurol Med,1989

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