Chronic inflammatory demyelinating polyradiculoneuropathy in chronic graft-versus-host disease following allogeneic hematopoietic stem cell transplantation: case report

Author:

Lorenzoni Paulo José1,Scola Rosana Herminia1,Carsten Ana Lucila Moreira1,Trentin Ana Paula1,Teive Hélio A.G.1,Pasquini Ricardo1,Werneck Lineu C.1

Affiliation:

1. Federal University of Paraná, Brazil

Abstract

The chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an unusual but important complication of hematopoietic stem cell transplantation (HSCT) rarely reported to date. We describe a 17-year-old woman with a diagnosis of acute myeloid leukemia due to Fanconi's anemia who was submitted to allogeneic HSCT and developed CIDP as part of graft-versus-host disease. Investigation showed high cerebrospinal fluid protein; electrophysiological studies revealed sensory-motor demyelinating polyradiculoneuropathy; muscle and nerve biopsy were compatible with CIDP.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Clinical Neurology

Reference21 articles.

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