Temporal pole signal abnormality on MR imaging in temporal lobe epilepsy with hippocampal sclerosis: a fluid-attenuated inversion-recovery study

Author:

Carrete Junior Henrique1,Abdala Nitamar2,Lin Kátia2,Caboclo Luís Otávio2,Centeno Ricardo Silva2,Sakamoto Américo Ceiki2,Szjenfeld Jacob2,Nogueira Roberto Gomes2,Yacubian Elza Márcia Targas2

Affiliation:

1. Universidade Federal de São Paulo, Brasil

2. UNIFESP

Abstract

OBJECTIVE: To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history. METHOD: Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation. RESULTS: Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy. CONCLUSION: Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Clinical Neurology

Reference24 articles.

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4. Relevance of temporal lobe white matter changes in hippocampal sclerosis: magnetic resonance imaging and histology;Meiners LC;Invest Radiol,1999

5. Anterior temporal abnormality in temporal lobe epilepsy: a quantitative MRI and histopathologic study;Mitchell LA;Neurology,1999

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