Orbital apex syndrome due to aspergillosis: case report

Author:

Fernandes Yvens B.1,Ramina Ricardo1,Borges Guilherme1,Queiroz Luciano S.1,Maldaun Marcos V.C.1,Maciel Jr. Jayme A.1

Affiliation:

1. Universidade Estadual de Campinas

Abstract

We report the case of a 73-year-old female who presented facial numbness and pain in the first division of the trigeminal nerve, ptosis, diplopia and visual loss on the right side for the previous four months. The neurological, radiological and histological examination demonstrated a rare case of invasive fungal aspergillosis of the central nervous system, causing orbital apex syndrome, later transformed in temporal brain abscess. She died ten months later due to respiratory and renal failure in spite of specific antimycotic therapy.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Reference14 articles.

1. Orbital apex syndrome;Bray WH;Surv Ophthalmol,1987

2. Optic neuropathy and paratrigeminal syndrome due to Aspergillus fumigatus;Weinstein JM;Ach Neurol,1982

3. Invasive aspergillosis;Denning DW;Clin Infect Dis,1998

4. Skull base osteitis following fungal sinusitis;Swift AC;J Laryngol Otol,1998

5. Itraconazole in the treatment of orbital aspergillosis;Massry GG;Ophthalmology,1996

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