Affiliation:
1. İstanbul University-Cerrahpasa, Turkey
Abstract
Abstract Background Deep vein thrombosis of the lower extremities is associated with a significant burden of comorbidities. Objectives In this study, our objective was to investigate the presence of seasonal variation in deep vein thrombosis (DVT) and assess the location of the thrombus. Methods Out of 8177 patients admitted to two university hospitals and referred to outpatient clinics, we included a total of 611 consecutive patients (316 females, 295 males) diagnosed with acute deep vein thrombosis in this retrospective study. The mean age of the patients was 59.35±18.49 years, ranging from 1 to 96 years. Patients were categorized into four groups by age. Results DVT was found to be more frequent in the summer (n = 190 or 31%, p = 0.003) and specifically in August (n = 65 or 10.6%, p = 0.014), while it was least frequent in the spring (n = 128 or 20.9%) and in May (n = 40 or 6.5%). However, when comparing seasons, no significant differences were observed in terms of seasonal variation (p = 0.062) or monthly variation (p = 0.143). Conclusions Contrary to previous studies, this study demonstrated a higher occurrence of DVT during the summer, particularly in August. However, it did not reveal a clear seasonal pattern. One plausible explanation for these findings could be the adverse winter conditions and transportation challenges within the province, which may result in fewer DVT patients being able to reach hospitals for timely treatment.
Subject
Cardiology and Cardiovascular Medicine
Reference19 articles.
1. Seasonal variation of venous thrombosis: a consecutive case series within studies from Leiden, Milan and Tromsø;Ribeiro DD;J Thromb Haemost,2012
2. Seasonal variation of venous thrombosis: a consecutive case series within studies from Leiden, Milan and Tromsø: a rebuttal;Christensen AL;J Thromb Haemost,2013
3. Seasonal and monthly variability in the incidence of venous thromboembolism: a systematic review and a meta-analysis of the literature;Dentali F;Thromb Haemost,2011
4. Deep vein thrombosis;Stubbs MJ;BMJ,2018
5. Age, and sex specific seasonal variation of venous thromboembolism in patients with and without family history: a nationwide family study in Sweden;Zöller B;Thromb Haemost,2013