Alprostadil associated with low molecular weight heparin to treat limb ischemia caused by SARS-CoV2

Author:

Manhanelli Filho Marcos Antonio Bonacorso1ORCID,Duarte Júnior Eliud Garcia2ORCID,Mariuba Jamil Victor de Oliveira3ORCID,Linardi Fábio1ORCID,Costa José Augusto3,Gali Julio Cesar3ORCID,Yoshida Winston Bonetti4ORCID,Gali Filho Julio Cesar5ORCID

Affiliation:

1. Pontifícia Universidade Católica de São Paulo, Brasil; Conjunto Hospitalar de Sorocaba, Brasil

2. Hospital Santa Mônica, Cirurgia Vascular e Endovascular, Brasil; Universidade Vila Velha, Brasil

3. Pontifícia Universidade Católica de São Paulo, Brasil

4. Universidade Estadual Paulista “Júlio de Mesquita Filho”, Brasil

5. JJMED, Brasil

Abstract

Abstract The current coronavirus pandemic has already taken a great toll globally, causing massive morbidity and mortality. One of its severe forms is a thrombophilic state that can damage several systems. This article reports the case of 60-year-old female patient who presented with mild flu symptoms, which turned out to be a SARS-CoV2 infection, and ended up developing arterial thrombosis with limb ischemia in a private care hospital in Sorocaba, São Paulo, Brazil. Considering this progression, we decided to intervene with low molecular weight heparin and Alprostadil, achieving a good clinical outcome. Our description aims to identify key points and clinical signs that offer evidence of the therapeutic window and a treatment option for coagulatory presentations of COVID-19.

Publisher

FapUNIFESP (SciELO)

Subject

Cardiology and Cardiovascular Medicine

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Acute Limb Ischemia in COVID-19: A Systematic Review;International Journal of Angiology;2023-08-14

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