Male with myelofibrosis and ulceronecrotic lesions

Author:

Santos Flávia da Silva Domingos1,Grupioni Priscila Vinhal1,Towersey Loan2,Bernardes Filho Fred3ORCID

Affiliation:

1. São Francisco Hospital, Brasil

2. Carlos Tortelly Municipal Hospital, Brasil

3. São Francisco Hospital, Brasil; University of São Paulo, Brasil

Abstract

SUMMARY Granulocytic sarcoma also called myeloid sarcoma is an extramedullary tumour of immature granulocytic cells. It is a rare entity, and mostly accompanied by acute myeloid leukaemia. It is observed during the course of myeloproliferative disorders especially in chronic myeloid leukaemia and myelodysplastic syndromes. Here, we report a case of a 60-year-old male with past history of myelofibrosis admitted to the emergency room due ulceronecrotic lesions, fever and dysphagia. We emphasize the importance of recognizing this entity and its severity.

Publisher

FapUNIFESP (SciELO)

Subject

General Medicine

Reference3 articles.

1. Cutaneous granulocytic sarcoma and Koebner phenomenon in a context of myelodysplastic syndrome;Nizery-Guermeur C;JAAD Case Rep,2015

2. An unusual type of myeloid sarcoma localization following myelofibrosis: a case report and literature review;Orofino N;Leuk Res Rep,2017

3. Prevalence and prognostic value of cutaneous manifestations in patients with myelodysplastic syndrome;Farah C;J Eur Acad Dermatol Venereol,2010

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