Histological study on acute inflammatory reaction to polyurethane-coated silicone implants in rats

Author:

Mendes Paulo Roberto da Silva1,Bins-Ely Jorge2,Lima Eduardo Arnaut dos Santos1,Vasconcellos Zulmar Antonio Accioli de2,d'Acampora Armando José3,Neves Rodrigo d' Eça4

Affiliation:

1. University Hospital, Brazil

2. UFSC, Brazil

3. UFSC, Brazil; Florianopolis Hospital, Brazil

4. UFSC, Brazil; University Hospital, Brazil

Abstract

PURPOSE: Evaluating histologically the silicone peri-implant coated by polyurethane inflammation associated to the use of anti-microbial and bacterial contamination. METHODS: It was used 35 Wistar rats. The animals were divided in seven groups: I - Control; II - implant cavity contamination with10 bacteria/ml; III - implant cavity contamination with 10 bacteria/ml; IV - implant cavity contamination with 10 bacteria/ml; V - identical contamination to group II and implant immersions in anti-microbial solution; VI - identical contamination in group III and implant immersions in the anti-microbial solution; VII - identical contamination of group IV and implant immersions in anti-microbial solution. It was evaluated morphometrically the peri-implant capsules after 30 days of introduction. RESULTS: The factors with more discriminating power were the giants cells of a strange body and the mononuclear. There was no correlation between the bacterial concentrations and the histological alterations. CONCLUSION: 1) The histological standard of the inflammatory reaction around the silicone implant coated with polyurethan is chronic granulomatosis type of a strange body; 2) There isn´t correlation between concentration of Staphylococcus epidermidis and histological changes; 3) The use of anti-microbial solution decreased the mononuclear cell reactions, with the increase of giant cells in a strange body.

Publisher

FapUNIFESP (SciELO)

Subject

Surgery

Reference15 articles.

1. Clinical Application of cross-linked dimethylpolysiloxane: restoration of breast, chest, atrophy of infantile paralysis, funnel-shaped chest, etc;Uchida J;JPN J Plast Reconstr Surg,1961

2. Complications of silicone injections;Kopf EH;Rocky Med J,1976

3. Management of patients with complications from injections of foreign material into the breast;Ortiz-Monasterio F;Plast Reconstr Surg.,1972

4. The influence of silicone bleed on capsular contracture;Caffe HH;Ann Plast Surg,1986

5. Polyurethane implants: a six year review of 416 patients;Melmed E;Plast Reconstr Surg,1988

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