OppA Escherichia coli mutants have osmodependent resistance to aminoglycoside antibiotics-Reference-Cited by-同舟云学术

OppA Escherichia coli mutants have osmodependent resistance to aminoglycoside antibiotics

Published:1998-03 Issue:1 Volume:21 Page:15-19
ISSN:1415-4757
Container-title:Genetics and Molecular Biology
language:
Short-container-title:Genet. Mol. Biol.

Author:

Tsuhako Maria H.¹,Ferreira Luis Carlos S.²,Costa Sérgio Olavo P. da¹

Affiliation:

1. Universidade de São Paulo

2. Universidade Federal do Rio de Janeiro

Abstract

The oligopeptide permease (OppA) protein was found to be missing in the periplasmic fractions of Escherichia coli kanamycin-resistant mutants selected under high osmotic conditions. The growth behavior of one mutant in media containing kanamycin or the toxic peptide triornithine suggests that OppA and another cell envelope component contribute to the osmolarity-dependent aminoglycoside resistance of E. Coli.

Publisher

FapUNIFESP (SciELO)

Subject

Genetics,Molecular Biology

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1. Spontaneous kanamycin-resistant Escherichia coli mutant with altered periplasmic oligopeptide permease protein (OppA) and impermeability to aminoglycosides;Revista de Microbiologia;1999-04