Challenges to improve the biopharmaceutical properties of poorly water-soluble drugs and the application of the solid dispersion technology

Author:

Tambosi Gabriela1,Coelho Paola Felippi2,Luciano Soares3,Lenschow Iára Cristina Schmücker1,Zétola Melissa1,Stulzer Hellen Karine2,Pezzini Bianca Ramos4

Affiliation:

1. Universidade da Região de Joinville, Brasil

2. Universidade Federal de Santa Catarina, Brasil

3. Universidade da Região de Joinville, Brasil; Universidade da Região de Joinville, Brasil

4. Universidade da Região de Joinville, Brasil; Universidade Federal de Santa Catarina, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

General Physics and Astronomy,General Materials Science,General Chemistry

Reference54 articles.

1. Formas farmacêuticas e sistemas de liberação de fármacos;ANSEL H.C,2013

2. An overview of clinical and commercial impact of drug delivery systems;ANSELMO A.C;Journal of Controlled Release,2014

3. Bridging solubility between drug discovery and development;DI L;Drug Discovery Today,2012

4. Drug-like properties and the causes of poor solubility and poor permeability;LIPINSKI C.A.;Journal of Pharmacological and Toxicological Methods,2000

5. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability;AMIDON G. L;Pharmaceutical Research,1995

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