Affiliation:
1. Universidade de São Paulo, Brazil
Abstract
ABSTRACT Objective: to identify and synthesize studies on the effects of cannabis use and its relation with SARS-CoV-2, as well as the therapeutic possibilities of using cannabinoids in the prevention and treatment of COVID-19. Methods: scoping review, in the BVS, PubMed, SCIELO, CINAHL, SCOPUS, Web of Science, MedNar, CAPES and ProQuest databases, with no language restriction and year limitation. Narrative synthesis was performed. Results: cannabis use causes changes in the respiratory and vascular system, it reduces the production of cytokines, which affects the users’ immune system, increasing the susceptibility to infection and progression of COVID-19. However, studies have suggested the use of cannabinoids in the prophylaxis and treatment of COVID-19, due to their anti-inflammatory effect. Conclusions: the use of inhaled cannabis increases the progression and severity of the infection. On the other hand, the benefits of cannabinoids seem promising to modulate the immune system, but it needs further studies.
Reference53 articles.
1. Painel do WHO Coronavirus Disease (COVID-19) [Internet],2020
2. A novel coronavirus from patients with pneumonia in China, 2019;Zhu N;N Engl J Med,2020
3. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study;Zhou F;Lancet,2020
4. Prolonged neuropsychological deficits, central nervous system involvement, and brain stem affection after COVID-19-A case series;Groiss SJ;Front Neurol,2020
5. MERS, SARS and other coronaviruses as causes of pneumonia;Yin Y;Respirology,2018
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