Affiliation:
1. Faculdade Terra Nordeste, Brazil
2. Universidade de Fortaleza, Brazil
3. Universidade Federal do Piauí, Brazil
4. Universidade Federal do Ceará, Brazil
Abstract
ABSTRACT Objectives: to identify the scientific evidence about the clinical complications and manifestations of congenital syphilis and aspects related to its prevention. Methods: integrative review after a search in the databases LILACS and MEDLINE, carried out in March 2018, using the descriptors “syphilis, congenital”, “complications”, and “signs and symptoms”, leading to the selection of 27 researches. Results: the publications found were published from 1966 to 2017, and most of them were from Latin America and Africa. Negative outcomes, laboratory changes, and the clinical manifestations in congenital syphilis, whether early or delayed, were, respectively: low weight at birth, anemia, hepatosplenomegaly, and dental alterations. The lack of treatment of the pregnant women in the prenatal was the most common occasion in which the opportunity to prevent the complications of congenital syphilis was lost. Conclusions: the scientific evidences analyzed showed serious complications of congenital syphilis that could be avoided if early opportunities of diagnosing and treating the pregnant women are not lost during the prenatal.
Reference39 articles.
1. The Global elimination of congenital syphilis: rationale and strategy for action [Internet],2007
2. Global guidance on criteria and processes for validation: elimination of mother-to-child transmission of HIV and syphilis [Internet],2014
3. Global burden of maternal and congenital syphilis in 2008 and 2012: a health systems modelling study;Wijesooriya NS;Lancet,2016
4. Guia sobre Desenvolvimento Sustentável: 17 objetivos para transformar o nosso mundo [Internet],2016
5. Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis;Gomez GB;Bull World Health Organ,2013
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献