Diagnostic approach in a patient with Creutzfeldt-Jakob disease-Reference-Cited by-同舟云学术

Diagnostic approach in a patient with Creutzfeldt-Jakob disease

Published:2022-09 Issue:3 Volume:16 Page:361-364
ISSN:1980-5764
Container-title:Dementia & Neuropsychologia
language:
Short-container-title:Dement. neuropsychol.

Author:

Tavares-Júnior José Wagner Leonel¹^ORCID,Carvalho Renata de Oliveira²^ORCID,Feitosa Raul Raposo Pereira³^ORCID,Rolim Flávia de Paiva Santos⁴^ORCID,Rocha Felipe Araújo³^ORCID,Pitombeira Milena Sales³^ORCID,Malveira George Linard Silva³^ORCID,Carvalho João José Freitas de³^ORCID,Frota Norberto Anizio Ferreira⁴^ORCID,Dias Daniel Aguiar¹^ORCID

Affiliation:

1. Universidade Federal do Ceará, Brazil

2. Hospital Monte Klinikum, Brazil

3. Hospital Geral de Fortaleza, Brazil

4. Hospital Geral de Fortaleza, Brazil; Universidade de Fortaleza, Brazil

Abstract

ABSTRACT Prion diseases are an important cause of rapidly progressive dementias. Among them, the most common is sporadic Creutzfeldt-Jakob disease (CJD). It is a rare and incurable disease, with rapid progression to death. Objective: To describe the diagnostic approach of a patient with Creutzfeldt-Jakob disease. Methods: The diagnosis is established through the clinical picture associated with characteristic changes in the brain magnetic resonance imaging, the electroencephalogram, and analysis of specific changes in the cerebrospinal fluid. Results: The present report describes the case of a 53-year-old patient in the city of Fortaleza-CE. The diagnosis was made based on the clinical condition and through diagnostic tests, including 14-3-3 protein and RT QUIC analysis. Differential diagnosis was performed with other rapidly progressive causes, such as infectious and immune-mediated diseases. Conclusions: The diagnosis of probable sporadic CJD was established.

Publisher

FapUNIFESP (SciELO)

Subject

Cognitive Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Neurology,Sensory Systems

Link

http://www.scielo.br/scielo.php?script=sci_pdf&pid=S1980-57642022000300361&tlng=en

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