IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?-Reference-Cited by-同舟云学术

IS THERE CORRELATION BETWEEN HUMAN PAPILLOMAVIRUS (HPV) AND ESOPHAGEAL EPIDERMOID CARCINOMA?

Published:2021 Issue:1 Volume:34 Page:
ISSN:2317-6326
Container-title:ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
language:
Short-container-title:ABCD, arq. bras. cir. dig.

Author:

WOELLNER Luiz Filipe Alkamin¹^ORCID,MEDEIROS Juliano Smaniotto de¹^ORCID,RIBAS Carmen Australia Paredes Marcondes¹^ORCID,NASSIF Paulo Afonso Nunes²^ORCID,RIBAS-FILHO Jurandir Marcondes²^ORCID,SOBRAL Ana Cristina Lira¹^ORCID,ARIEDE Bruno Luiz³^ORCID,COSTA Debora Azeredo Pacheco Dias DA³^ORCID,MALAFAIA Osvaldo²^ORCID

Affiliation:

1. Mackenzie Evangelical Faculty of Paraná, Brazil

2. Mackenzie Evangelical Faculty of Paraná, Brazil; Faculdade Evangélica Mackenzie do Paraná, Brazil; Evangelical University Mackenzie Hospital, Brazil

3. Faculdade Evangélica Mackenzie do Paraná, Brazil

Abstract

ABSTRACT Background: Currently, persistent human papillomavirus (HPV) infection has been related in some geographic regions as a risk factor for esophageal squamous cell carcinoma. It results in the immunoexpression of the p16 protein, which has been used as marker of the oncogenic lineage by this etiological agent. Aim: To correlate epidemiological aspects of esophageal squamous cell carcinoma with the prevalence of HPV infection. Methods: Fifty-eight cases were analyzed and submitted to histopathological and immunohistochemical analysis by p16. Results: Of the 58 cases evaluated, 40 were men and 18 women, with a mean age of 63.2 years. p16 immunoexpression was positive in 46.55%. Conclusion: The prevalence of HPV infection is high in esophageal squamous cell carcinoma presenting in almost half of the cases (46.55%), without gender differentiation.

Publisher

FapUNIFESP (SciELO)

Subject

General Medicine

Link

http://www.scielo.br/pdf/abcd/v34n1/0102-6720-abcd-34-01-e1528.pdf

Reference21 articles.

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1. PRESENÇA DO PAPILOMAVIRUS HUMANO TIPO 16 E EXPRESSÃO GÊNICA DA PROTEÍNA P16INK4A E ONCOPROTEÍNA E7 NO CARCINOMA COLORRETAL;ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo);2021