The small bowel flora in individuals with cecoileal reflux

Author:

Machado Wellington Monteiro1,Miranda José Ricardo Arruda2,Morceli José1,Padovani Carlos Roberto2

Affiliation:

1. Paulista State University

2. UNESP, Brazil

Abstract

BACKGROUND: The observation of cecoileal reflux to barium enema is not rare; however, its causes and consequences have not been widely investigated. Considering that ileocecal junction exerts a function as barrier to invasion of bacteria from colon to small bowel, it seems interesting to study the intestinal microflora in subjects carrying cecoileal reflux. AIMS: This study aims at evaluating the ileal flora in individuals with cecoileal reflux. METHODS: A group of 36 subjects comprising 30 females and 6 males with a mean age of 54 years was assessed. Twenty-five individuals with cecoileal reflux and 11 without cecoileal reflux were submitted to small intestine contamination evaluation through the breath test with lactulose-H2 and measurement of the orocecal transit time by means of alternate current biosusceptometry. Small intestine bacterial overgrowth was characterized by orocecal transit time-H2 shortening. RESULTS: Comparison of basal H2, orocecal transit time-H2 and orocecal transit time-alternate current biosusceptometry measurements did not statistically differ between the groups with and without cecoileal reflux. Orocecal transit time-H2 was significantly smaller than orocecal transit time-alternate current biosusceptometry, particularly in individuals with cecoileal reflux. A significant correlation between the two methods was observed only in relation to control, not existing in relation to cecoileal reflux group. CONCLUSIONS: Smaller orocecal transit time-H2 and the loss of correlation with orocecal transit time-alternate current biosusceptometry observed in the individuals with cecoileal reflux suggest a differentiated behavior for such group relative to control, which could be associated with small intestine bacterial overgrowth.

Publisher

FapUNIFESP (SciELO)

Subject

Gastroenterology

Reference54 articles.

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3. Ileo-cecal junction: a valve or a sphincter? An experimental study in the opossum;Calabuig R;Rev Esp Enferm Dig,1996

4. Repeatability of lactulose hydrogen breath test in subjects with normal or prolonged orocecal transit;Camboni G;Dig Dis Sci,1988

5. Manometric characteristics of the human ileocecal junctional zone;Cohen S;Gastroenterology,1968

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