Metabolism of fat in subacute combined degeneration of the spinal cord

Author:

Canelas Horacio M.,Carvalho Nelson de1,Rocha Arnaldo Gama da

Affiliation:

1. University of São Paulo

Abstract

In 10 cases of subacute combined degeneration of the spinal cord the absorption, clearance and utilization of labeled fat was studied. In 4 cases disorders of the lipid metabolism were found. Although not significantly, the peripheral and dorsal funiculi syndromes were more severe in the 4 cases with impaired fat metabolism than in the normal cases, while the pyramidal syndrome was almost the same in the two groups. The whole neurological picture was also more severe in the 4 cases with disorders of fat metabolism. These results seem to indicate that the impairment of lipid metabolism evidenced in such cases bears no direct relationship with the demyelinating process in general, and would rather attend a deficiency of metabolites (probably B-complex vitamins) other than vitamin B12, which play a more significant role in the preservation of the peripheral nerves.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Clinical Neurology

Reference25 articles.

1. Neurochemistr'y;ADAMS C. W. M.,1962

2. The preparation and some properties of purified myelin from the central nervous system;AUTILIO L. A.;J. Neurochem.,1964

3. Serum fatty acids in multiple sclerosis;BAKER R. W. R.;J. Neurol. Neurosurg. Psychiat.,1964

4. Phospholipid fractions in multiple sclerosis and normal serum;BERNSOHN J.;Proc. Soc. exp. Biol.,1955

5. Lipóides e fósforo inorgânico humorais na neuranemia;CANELAS H. M.;Arq. Neuro-psiquiat.,1950

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