HBV and HCV serological markers in patients with the hepatosplenic form of mansonic schistosomiasis

Author:

Silva Jéfferson Luis de Almeida1,Souza Veridiana Sales Barbosa de1,Vilella Tatiana Aguiar Santos1,Domingues Ana Lúcia C.2,Coêlho Maria Rosângela Cunha Duarte3

Affiliation:

1. Federal University of Pernambuco

2. UFPE

3. Federal University of Pernambuco; UFPE

Abstract

CONTEXT: Blood transfusion is one of the major risk factors for the transmission of the hepatitis B (HBV) and C (HCV) viruses. However, there are no reports describing the endoscopic transmission of these viruses in patients with the hepatosplenic form of schistosomiasis. OBJECTIVE: To estimate the prevalence of serological markers of HBV and HCV in patients with the hepatosplenic form of schistosomiasis and evaluate the possible risk factors associated with these infections. METHODS: A cross-sectional study was conducted on 230 patients with hepatosplenic form of schistosomiasis who attended a university hospital in Recife, Northeastern Brazil, from February to August 2008. The patients answered a standardized questionnaire about risk factors. Serum samples were analyzed for anti-HBc total, anti-HBs, HBsAg, and anti-HCV using enzyme-linked immunosorbent assays. Univariate analysis and multiple logistic regression were performed. RESULTS: The prevalence was 30% for anti-HBc total and/or HBsAg and 7.4% for anti-HCV. There was a higher frequency of the serological markers in females and in patients aged .50 years. A significant association was detected between the presence of anti-HCV and the receipt of six or more blood transfusions. There was no association of history and number of digestive endoscopies with the serological markers analyzed. CONCLUSIONS: We observed a higher prevalence of serological markers for HBV and a lower prevalence of anti-HCV. Our results indicate that females and patients of an advanced age are the most affected categories and that patients that received multiple transfusions are at a higher probability of HCV infection.

Publisher

FapUNIFESP (SciELO)

Subject

Gastroenterology

Reference32 articles.

1. Chronic liver disease in the Alexandria governorate, Egypt: contribution of schistosomiasis and hepatitis infections;Angelico M;J Hepatol,1997

2. Hepatitis B and C virus markers among patients with hepatosplenic mansonic schistosomiasis;Aquino RT;Rev Inst Med Trop São Paulo,2000

3. Clínica e cirurgia;Barreto VST,1996

4. [Hepatitis C virus contamination of endoscopes and biopsy forceps].;Bécheur H;Gastroenterol Clin Biol,2000

5. A prospective study of the efficacy of routine decontamination for gastrointestinal endoscopes and the risk factors for failure;Bisset L;Am J Infect Control,2006

Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Meta‐analysis: risk of hepatitis C virus infection associated with hospital‐based invasive procedures;Alimentary Pharmacology & Therapeutics;2022-06-27

2. Machine learning algorithms to predict the 1 year unfavourable prognosis for advanced schistosomiasis;International Journal for Parasitology;2021-10

3. Hepatosplenic schistosomiasis, the ignored morbidity: experience from a referral hospital in Ethiopia;Transactions of The Royal Society of Tropical Medicine and Hygiene;2020-09-03

4. Spatial analysis of viral hepatitis and schistosomiasis coinfection in an endemic area in Northeastern Brazil;Revista da Sociedade Brasileira de Medicina Tropical;2017-06

5. Hepatitis B and Schistosoma co-infection in a non-endemic area;European Journal of Clinical Microbiology & Infectious Diseases;2016-06-07

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3