AGE AND GENDER MAY INFLUENCE THE RESULTS OF ROUX-EN-Y GASTRIC BYPASS? Metabolic syndrome parameters

Author:

ANDRADE-SILVA Stephan Garcia1,CARANTI Danielle Arisa2,SALLET José Afonso3,LEAL Lucas Pedroso Fernandes Ferreira4,LEAL Antonio Joaquim Ferreira3,DÂMASO Ana Raimunda5

Affiliation:

1. Universidade Federal de São Paulo - UNIFESP, Brasil; Universidade Federal de São Paulo - UNIFESP, Brasil; CliLeal - Clínica Médica e Cirurgia Geral, Brasil

2. Universidade Federal de São Paulo - UNIFESP, Brasil; Universidade Federal de São Paulo - UNIFESP, Brasil; Universidade Federal de São Paulo - UNIFESP, Brasil

3. CliLeal - Clínica Médica e Cirurgia Geral, Brasil

4. Universidade Federal de São Paulo - UNIFESP, Brasil; CliLeal - Clínica Médica e Cirurgia Geral, Brasil

5. Universidade Federal de São Paulo - UNIFESP, Brasil; Universidade Federal de São Paulo - UNIFESP, Brasil; Universidade Federal de São Paulo - UNIFESP, Brasil; Universidade Federal de São Paulo - UNIFESP, Brasil

Abstract

Context Severe obesity affects the body favoring the development of serious diseases, including hypertension, diabetes mellitus, atherosclerosis and non alcoholic fatty liver disease. Bariatric procedures increased in Brazil in the last decade. Objectives The purpose of this study was to verify if gender and age in date of procedure resulted significant differences in metabolic syndrome parameters after surgery. Methods The study involved 205 medical records of adult patients undergoing Roux-en-Y gastric bypass, stratified by gender and age groups and followed one year by a multidisciplinary team. Results It was observed significant decrease in body mass index, fasting glucose and insulin at all ages and both genders. Lipid profile showed significant improvements except high density lipoprotein cholesterol. Ectopic fat in the liver has decreased after 6 months in patients classified with steatosis at baseline. Patients classified as hypertensive blood pressure levels decreased 6 months after surgical intervention. Conclusions Roux-en-Y gastric bypass proved to be an important tool in remission of metabolic syndrome parameters. The reduction of body mass accompanied to decrease in insulin resistance resulted in lower prevalence of comorbidities associated with obesity. The benefits were similar and extended both genders and all age groups between 18 and 65 years old.

Publisher

FapUNIFESP (SciELO)

Subject

Gastroenterology

Reference54 articles.

1. Laparoscopic Roux-en-Y gastric bypass and its early effect on blood pressure;Ahmed AR;Obes Surg,2009

2. Diabetes resolution and hyperinsulinaemia after metabolic Roux-en-Y gastric bypass;Ashrafian H;Obes Rev,2011

3. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women;Asztalos BF;J Lipid Res,2010

4. Doença hepática gordurosa não alcoólica: características clínicas e histológicas em obesos graves submetidos à cirurgia bariátrica;Cotrim HP;Acta Gastroenterol Latinoam,2007

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