Pharmacological blockade of protease-Activated Receptor 2 improves airway remodeling and lung inflammation in experimental allergic asthma
Author:
Affiliation:
1. Federal University of Ouro Preto, Brazil; Federal University of Minas Gerais, Brazil
2. Federal University of Minas Gerais, Brazil
Publisher
FapUNIFESP (SciELO)
Link
http://www.scielo.br/scielo.php?script=sci_pdf&pid=S1984-82502022000100871&tlng=en
Reference40 articles.
1. Structure, function and pathophysiology of protease activated receptors;Adams MN;Pharmacol Ther,2011
2. Remodeling in asthma;Al-Muhsen S;J Allergy Clin Immunol,2011
3. Mucosal allergic sensitization to cockroach allergens is dependent on proteinase activity and proteinase-activated receptor-2 activation;Arizmendi NG;J Immunol,2011
4. Proteinase-activated receptor-2 blockade inhibits changes seen in a chronic murine asthma model;Asaduzzaman M;Allergy,2018
5. Functional inhibition of PAR2 alleviates allergen-induced airway hyperresponsiveness and inflammation;Asaduzzaman M;Clin Exp Allergy,2015
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