Validation of a method for simultaneous analysis of cocaine, benzoylecognine and cocaethylene in urine using gas chromatography-mass spectrometry

Author:

Menotti Vinicius Stela1,Scanferla Deborah Thais Palma1,Oliveira Kleber Ota de1,Fratucci Gabriela Felber1,Alves Gessé de Souza1,Bando Erika1,Nerilo Samuel Botião2,Oliveira Magda Lúcia Félix de1,Machinski Junior Miguel1,Mossini Simone Aparecida Galerani3ORCID

Affiliation:

1. State University of Maringa, Brazil

2. State University of Maringa, Brazil; University Center Ingá, Brazil

3. State University of Maringa, Brazil; State University of Maringa, Brazil

Publisher

FapUNIFESP (SciELO)

Reference23 articles.

1. Guia para Validação de Métodos Analíticos e Bioanalíticos,2012

2. Determination of Cocaine and Its Major Metabolite Benzoylecgonine in Several Matrices Obtained from Deceased Individuals with Presumed Drug Consumption prior to Death;Alvear E;J Foren Legal Med.,2014

3. Determination of Opiates and Cocaine in Urine by High pH Mobile Phase Reversed Phase UPLC-MS/MS;Berg T;J Chrom B: Anal Techn Biomed Life Sci,2009

4. An optimized gc-ms method for identification of cocaine and its major metabolites;Bonchev G;Journal of IMAB - Annual Proceeding (Scientific Papers),2017

5. Determination of Cocaine and Benzoylecgonine by Direct Injection of Human Urine into a Column-Switching Liquid Chromatography System with Diode-Array Detection;Brunetto MR;J Pharm Biomed Anal.,2015

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