HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil

Author:

Dourado Inês1,Milroy Craig A.1,Mello Marco Antônio Gomes2,Ferraro Geraldo Argolo2,Castro-Lima Filho Humberto2,Guimarães Monick Lindenmeyer3,Morgado Mariza Gonçalves3,Teixeira Maria Gloria1,Barreto Maurício L.1,Galvão-Castro Bernardo2

Affiliation:

1. Universidade Federal da Bahia, Brasil

2. Fundação Oswaldo Cruz, Brasil; Fundação Bahiana para o Desenvolvimento das Ciências, Brasil

3. Fundação Oswaldo Cruz, Brasil

Abstract

To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750.

Publisher

FapUNIFESP (SciELO)

Subject

Public Health, Environmental and Occupational Health

Reference29 articles.

1. Pneumocystis pneumonia - Los Angeles;MMWR Morb Mortal Wkly Rep,1981

2. Isolation of a T-lymphotropic retrovirus from a patient at risk for acquired immune deficiency syndrome (AIDS);Barre-Sinoussi F;Science,1983

3. Boletim Epidemiológico AIDST 2004

4. Análise sociodemográfica da epidemia de Aids no Brasil, 1989-1997;Fonseca MGP;Rev Saúde Pública,2002

5. Distribuição social da AIDS no Brasil, segundo participação no mercado de trabalho, ocupação e status sócio-econômico dos casos de 1987-1998;Fonseca MGP;Cad Saúde Pública,2003

Cited by 16 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3