Affiliation:
1. Universidade Federal de Minas Gerais, Brazil
Abstract
ABSTRACT Hematological and biochemical alterations in animals with neoplasms may result from the direct effects of tumor growth or paraneoplastic syndromes. The objective of this study was to evaluate these hematological and biochemical alterations in female dogs with mammary tumors and with inflammatory carcinoma (IC). Blood samples were collected from 43 female dogs divided into three groups according to clinical staging: Group 1 (G1) - animals in initial stage (T1,2,3N0M0, N=17), Group 2 (G2) - animals in advanced stage (T1,2,3N1M0,1, N=15) and Group 3 (G3) - animals presenting IC (N=11). Hematological and biochemical parameters obtained were related to patients' clinical staging. Among alterations, the most common were anemia, neutrophilic leukocytosis, monocytosis, increased ALT, AST, and hypoalbuminemia, mainly in dogs in advanced clinical staging and with inflammatory carcinoma.
Reference27 articles.
1. Veterinary hematology and clinical chemistry;ALLISON R.W,2012
2. Small animal clinical oncology;BAILEY D.B,2020
3. Inflammation and cancer: back to Virchow;BALKWILL F.;Lancet,2001
4. Unexplained high AST in locally advanced breast cancer;BIRTLE A.;Breast,2003
5. Cancer-related anemia: Biological findings, clinical implications and impact on quality of life;BLOHMER J.;Oncology,2005
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献