Bullous pemphigoid in a 3-month-old infant: case report and literature review of this dermatosis in childhood

Author:

Reis-Filho Eugenio Galdino de Mendonça1,Silva Tainah de Almeida2,Aguirre Luiza Helena de Lima2,Reis Carmelia Matos Santiago3

Affiliation:

1. Brasilia Catholic University; Distrito Federal Health State Secretariat, Brazil

2. Asa Norte Regional Hospital, Brazil

3. Brasilia Catholic University; Asa Norte Regional Hospital, Brazil

Abstract

Bullous pemphigoid is an autoimmune subepidermal blistering dermatosis that is uncommon in childhood. We report a case of a female infant, 3 months old, which presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. The authors used immunohistochemical staining for collagen type IV that allowed the differentiation of bullous pemphigoid from other subepidermal bullous diseases. Opportunely we review the clinical, immunological, therapeutic and prognostic features of this pathology in children.

Publisher

FapUNIFESP (SciELO)

Subject

Dermatology

Reference23 articles.

1. Clinical features and practical diagnosis of bullous pemphigoid;Schmidt E;Immunol Allergy Clin North Am,2012

2. Bullous pemphigoid: From the clinic to the bench;Di Zenzo G;Clin Dermatol,2012

3. Bullous pemphigoid in children. Report of three cases with special emphasis on therapy;Oranje AP;Int J Dermatol,1991

4. Childhood bullous pemphigoid. Clinical and immunologic features, treatment, and prognosis;Nemeth AJ;Arch Dermatol,1991

5. Bullous pemphigoid in infancy developing after the first vaccination;Hafiji J;Clin Exp Dermatol,2010

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