Affiliation:
1. Sao Paulo State University, Brazil
Abstract
Histoplasmosis is a systemic mycosis endemic in extensive areas of the Americas. The authors report on an urban adult male patient with uncommon oral-cutaneous lesions proven to be histoplasmosis. Additional investigation revealed unnoticed HIV infection with CD4+ cell count of 7/mm3. The treatment was performed with amphotericin B, a 2065 mg total dose followed by itraconazole 200mg/daily plus antiretroviral therapy with apparent cure. Histoplasmosis is an AIDS-defining opportunistic disease process; therefore, its clinical diagnosis must drive full laboratory investigation looking for unnoted HIV-infection.
Reference10 articles.
1. Histoplasmosis: a clinical and laboratory up-date;Kauffman CA;Clin Microbiol Rev,2007
2. Histoplasma capsulatum at the host-pathogen interface;Nosanchuk JD;Microbes Infect,2008
3. Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. Council of State and Territorial Epidemiologists; AIDS Program, Center for Infectious Diseases;MMWR,1987
4. Histoplasmosis in the acquired immunodeficiency syndrome;Wheat L;Curr Top Med Mycol,1996
5. Mucocutaneous manifestations of disseminated histoplasmosis in patients with acquired immunodeficiency syndrome: particular aspects in a Latin-American population;Cunha VS;Clin Dermatol,2009
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献