Affiliation:
1. Hospital Center at Porto, Portugal
Abstract
Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and may go unrecognized. Due to the paucity of reports of Crohn's disease at this location and in the absence of randomized trials, there are no standard treatments for the cutaneous disease. We describe the case of a 47 year-old woman with vulvoperineal Crohn's disease without digestive involvement, that was successfully managed with metronidazole.
Reference8 articles.
1. Crohn's disease: an important differential diagnosis of granulomatous skin diseases;Eames T;Eur J Dermatol,2009
2. Crohn's disease of the vulva;Andreani SM;Int J Surg,2010
3. Isolated Crohn's disease of the vulva;Madnani NA;Indian J Dermatol Venereol Leprol,2011
4. Vulvoperineal Crohn's disease: response to metronidazole;Khaled A;Skinmed,2010
5. Metastatic Crohn disease: clearance with metronidazole;Abide JM;J Am Acad Dermatol,2011
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献