Beta therapy with 90strontium as single modality therapy for canine squamous cell carcinoma in third eyelid

Author:

Andrade Alexandre Lima de1,Fernandes Marco Antônio Rodrigues2,Sakamoto Silmara Sanae2,Luvizotto Maria Cecília Rui1

Affiliation:

1. Universidade Estadual Paulista "Júlio de Mesquita Filho", Brazil

2. UNESP, Brazil

Abstract

The purpose was to evaluate the effectiveness of beta-radiation with strontium-90 as single modality treatment of canine third eyelid squamous cell carcinoma (SCC). Nine dogs diagnosed with third eyelid SCC were treated with strontium-90. Radiation therapy was administered in four fractions of 100cGy per site every four days and at a depth of 0.2cm (Strontium-90 build' up) in each fraction. Radiation with beta therapy was well tolerated in all animals with no occurrence of radiation induced cataracts. In all cases, there were increased signs of conjunctival inflammation around the mass, which subsided with topical anti-inflammatory. Two dogs required surgical treatment for local tumor recurrence at 150 days and 352 days. In the remaining seven cases, disease free interval ranged from 1239 days to 2555 days. Beta therapy using 90Sr may be a valid alternative for the treatment of third eyelid SCC in dogs

Publisher

FapUNIFESP (SciELO)

Subject

General Veterinary,Agronomy and Crop Science,Animal Science and Zoology

Reference27 articles.

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4. Canine limbal melanoma: 30 cases (1992-2004). Part 2. Treatment with lamellar resection and adjunctive strontium-90 beta plesiotherapy - efficacy and morbidity;DONALDSON D.;Veterinary Ophthalmology,2006

5. Angiokeratoma - a benign vascular tumor of the dog;GEORGE C.;Journal of Small Animal Practice,1990

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