Anthraquinones from the bark of Senna macranthera

Author:

Branco Alexsandro1,Pinto Angelo C.2,Schripsema Jan3,Braz-Filho Raimundo3

Affiliation:

1. Universidade Estadual de Feira de Santana

2. Universidade Federal do Rio de Janeiro, Brasil

3. Universidade Estadual do Norte Fluminense Darcy Ribeiro, Brasil

Abstract

2-acetyl physcion (2-acetyl-1,8-dihydroxy-6-methoxy-3-methyl-9,10-anthraquinone, 2), a rare anthraquinone, was isolated from Senna macranthera var. nervosa (Vogel) H.S. Irwin & Barneby (Fabaceae). The chemical structure was elucidated and all ¹H and 13C NMR chemical shifts were assigned by NMR one- (¹HNMR, {¹H}-13CNMR, and APT-13CNMR) and two (COSY, NOESY, HMQC and HMBC) dimensional of this natural compound. Furthermore, the minor anthraquinones chrysophanol (3), chrysophanol-8-methyl ether (4) and physcion (5) were characterized by GC-MS analysis. The occurrence of the anthraquinones 3-5 confirms that S. macranthera is a typical representative of the genus Senna.

Publisher

FapUNIFESP (SciELO)

Subject

Multidisciplinary

Reference20 articles.

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4. Rubrofusarina, um policetídeo natural inibidor da topoisomerase II-α humana;BRANCO A;Rev Bras Farmacogn,2008

5. Elementos de fitoquímica y de farmacognosia;BRUNETON J,1991

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