Affiliation:
1. Universidade Federal do Rio de Janeiro, Brazil
2. Jardim Botânico do Rio de Janeiro, Brazil
Abstract
The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant effects in the tested animals.
Reference21 articles.
1. Identification of Essential Oil Components by Gas Chromatography/ Mass Spectroscopy;ADAMS RP,1995
2. Cytotoxicity and radical intensity of eugenol, isoeugenol or related dimers;ATSUMI T;Anticancer Research,,2000
3. Variations in the volatile constituents of Peperomia rotundifolia Schlecht. & Cham. Grown on different host-trees in Guadeloupe;BESSIERE JM;Flav Fragr J,1994
4. Dicionário das Plantas Úteis do Brasil e das Exóticas Cultivadas;CORRÊA MP,1984
5. Handbook of Medicinal Herbs;DUKE JA,1985
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