Dosage of heparin for patency of the totally implanted central venous catheter in cancer patients

Author:

Oliveira Francisca Jane Gomes de1ORCID,Rodrigues Andrea Bezerra2ORCID,Ramos Islane Costa3ORCID,Caetano Joselany Áfio3ORCID

Affiliation:

1. Universidade Federal do Ceará, Brazil; Hospital Monte Klinikum, Brazil

2. Hospital Universitário Walter Cantídio, Brazil

3. Universidade Federal do Ceará, Brazil

Abstract

Objective: to analyze the evidence available in the literature about the lowest necessary dose of heparin to maintain the patency of the totally implanted central venous catheter in adult cancer patients. Method: an integrative literature review, carried out in the following databases: Literatura Latino-Americana e do Caribe em Ciências de Saúde, Sciverse Scopus, Web of Science, Cumulative Index to Nursing and Allied Health Literature, Cochrane Central Register of Controlled Trials, including thirteen studies. Results: the evidence showed that the dose of heparin (300 IU/ml) is the most used in maintaining the patency of the totally implanted central venous catheter. Conclusion: according to the selected studies, the lowest dose of heparin found in maintaining the patency of the totally implanted central venous catheter in cancer patients was 10 UN/ml with a volume of 5 ml of the heparin solution.

Publisher

FapUNIFESP (SciELO)

Reference44 articles.

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3. Maintaining patency in totally implantable venous access devices (TIVAD): a time-to-event analysis of different lock irrigation intervals;Palese A;Eur J Oncol Nurs,2014

4. Infusion nursing standards of practice;J Infus Nurs,2016

5. Occlusion management guideline for central venous access devices (CVADs);Hill J;Vasc Access,2013

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