Affiliation:
1. Universidade Federal do Espírito Santo, Brazil
Abstract
In order to evaluate melatonin implication in the regulating of its own secretory process by pinealocytes, we used morphometric techniques for transmission electron microscopy. In mice treated with 100 mg of melatonin (N-acetyl-5-methoxy-tryptamine) by daily subcutaneous injection, we observed a decrease in number and volumetric density of lysosomes. Our results showed that melatonin influences the secretory activity of pinealocytes and participates in a complex secretory regulating mechanism.
Subject
General Agricultural and Biological Sciences
Reference26 articles.
1. Melatonin and the pineal gland: influence on mammalian seasonal and circadian physiology;ARENDT J.;Reviews of Reproduction,1998
2. Comprehensive Endocrinology: The Pineal Gland;CARDINALI D. P.,1984
3. Time and time again: the phylogeny of melatonin as a transducer of biological time;CASSONE V. M.;J. Biol. Rhythms,1997
4. Neuronal secretory systems;CASTEL M.;Int. Rev. Cytol.,1984
5. Advances in Pineal Research;COLLIN J. P.,1986
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献