Phenytoin-Induced Gingival Overgrowth Management with Periodontal Treatment

Author:

Gurgel Bruno César de Vasconcelos1,Morais Carlos Roberto Batista de1,Rocha-Neto Pedro Carlos da1,Dantas Euler Maciel1,Pinto Leão Pereira1,Costa Antonio de Lisboa Lopes1

Affiliation:

1. UFRN - Federal University of Rio Grande do Norte, Brazil

Abstract

Phenytoin-induced gingival overgrowth (PIGO) is a common complication of the continuous use of medications. This paper presents a case of PIGO hindering oral function and compromising oral hygiene and aesthetics, which was treated with a combination of nonsurgical and surgical periodontal therapies. A 39-year-old male patient was referred for dental treatment with several complaints, especially upper and lower gingival overgrowth that hindered speech and swallowing. Generalized deep probing pockets and bone loss were detected. Diagnosis of gingival overgrowth associated with phenytoin and chronic periodontitis was established. The treatment plan consisted of conservative therapy with education on oral health, motivation and meticulous oral hygiene instruction in combination with scaling and root planing. During the revaluation period, a marked reduction in the clinical parameters was noted, particularly probing pocket depth reduction. Surgical therapy for removal of gingival overgrowth was also performed to achieve pocket reduction. Supportive periodontal therapy was proposed and the patient is currently under follow-up for 4 years. Management of PIGO may be obtained by the use of periodontal procedures combined with good oral hygiene and periodontal supportive care.

Publisher

FapUNIFESP (SciELO)

Subject

General Dentistry

Reference25 articles.

1. Phenobarbital-induced gingival hyperplasia;Lafzi A,;J Contemp Dent Pract,2007

2. Phenytoin-induced gingival overgrowth: a review of the molecular, immune, and inflammatory features;Corrêa JD;ISRN Dent,2011

3. Connective tissue metabolism and gingival overgrowth;Trackman PC;Crit Rev Oral Biol Med,2004

4. Drug-induced gingival overgrowth - a review;Kataoka M;Biol Pharm Bull,2005

5. Impaired degradation of matrix collagen in human gingival fibroblasts by the antiepileptic drug phenytoin;Kato T;J Periodontol,2005

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Dental management of a child patient with phenytoin-induced gingival overgrowth: report of a case with a brief review of literature;Journal of Dental Health, Oral Disorders & Therapy;2023

2. Management of medication-induced gingival hyperplasia: a systematic review;Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology;2021-01

3. Boronic acid functionalized graphene platforms for diabetic wound healing;Carbon;2020-03

4. Phenytoin-induced gingival hyperplasia;Erciyes Medical Journal;2019

5. Peters-plus syndrome: oral health approach;Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial;2018-12-30

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3