Estudo comparativo entre miltefosina oral e antimoniato de N-metil glucamina parenteral no tratamento da leishmaniose experimental causada por Leishmania (Leishmania) amazonensis-Reference-Cited by-同舟云学术

Estudo comparativo entre miltefosina oral e antimoniato de N-metil glucamina parenteral no tratamento da leishmaniose experimental causada por Leishmania (Leishmania) amazonensis

Published:2008-08 Issue:4 Volume:41 Page:424-427
ISSN:0037-8682
Container-title:Revista da Sociedade Brasileira de Medicina Tropical
language:
Short-container-title:Rev. Soc. Bras. Med. Trop.

Author:

Costa Filho Arnoldo Velloso da¹,Lucas Íris Campos¹,Sampaio Raimunda Nonata Ribeiro¹

Affiliation:

1. Universidade de Brasília

Abstract

Vinte e cinco camundongos infectados com Leishmania amazonensis foram tratados com antimoniato de N-metil glucamina e miltefosina oral. Critérios: medidas das patas, pesquisa de amastigotas e culturas após-tratamento. Miltefosina: 2,43mm e glucamina 3,46mm (p=0,05). Miltefosina: esfregaços e culturas negativos. Glucamina: 2 esfregaços positivos e culturas positivas (p<0,05). Concluímos que miltefosina foi semelhante à glucamina.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,Microbiology (medical),Parasitology

Link

http://www.scielo.br/pdf/rsbmt/v41n4/a22v41n4.pdf

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