The genus Brucella and clinical manifestations of brucellosis

Abstract

Infection with bacteria of the genus Brucella results in major economic and political impact by causing reproductive diseases in a significant number of domestic animal species. Moreover, it has a great social significance, since many species are capable of causing human infection, with severe consequences. Dissemination of knowledge on a specific disease is an essential step for its control. Considering that brucellosis is still the most prevalent zoonosis in the world, information about taxonomy, clinical signs in domestic animals and humans are crucial for attempting to reduce the prevalence of this disease. The recent isolation and characterization of non-classical species of Brucella indicates that a lot remains to be discovered about this genus. Nevertheless, due to the social-economic importance of brucellosis, this review aims to clarify points related to taxonomy of the genus and describe the clinical relevance of infection in humans and domestic animals.