Primary neural leprosy: systematic review-Reference-Cited by-同舟云学术

Primary neural leprosy: systematic review

Published:2013-06 Issue:6 Volume:71 Page:397-404
ISSN:0004-282X
Container-title:Arquivos de Neuro-Psiquiatria
language:
Short-container-title:Arq. Neuro-Psiquiatr.

Author:

Garbino Jose Antonio¹,Marques Jr Wilson²,Barreto Jaison Antonio¹,Heise Carlos Otto³,Rodrigues Marcia Maria Jardim⁴,Antunes Sergio L.⁴,Soares Cleverson Teixeira¹,Floriano Marcos Cesar⁵,Nery Jose Augusto⁴,Trindade Maria Angela Bianconcini¹,Carvalho Noemia Barbosa⁶,Andrada Nathalia Carvalho de⁶,Barreira Amilton Antunes²,Virmond Marcos da Cunha Lopes¹

Affiliation:

1. Secretaria de Estado de Saude, Brazil

2. Universidade de Sao Paulo (USP), Brazil

3. USP, Brazil

4. Fundacao Oswaldo Cruz, Brazil

5. Universidade Federal de Sao Paulo (Unifesp), Brazil

6. Conselho Federal de Medicina, Brazil

Abstract

The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels of scientific evidence according to the “Oxford Centre for Evidence-based Medicine”. The following aspects were reviewed: cutaneous clinical and laboratorial investigations, i.e. skin clinical exam, smears, and biopsy, and Mitsuda's reaction; neurological investigation (anamnesis, electromyography and nerve biopsy); serological investigation and molecular testing, i.e. serological testing for the detection of the phenolic glycolipid 1 (PGL-I) and the polymerase chain reaction (PCR); and treatment (classification criteria for the definition of specific treatment, steroid treatment, and cure criteria).

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Link

http://www.scielo.br/pdf/anp/v71n6/0004-282X-anp-71-06-397.pdf

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