Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder

Author:

Fragoso Yara Dadalti1,Adoni Tarso2,Brooks Joseph Bruno Bidin1,Gomes Sidney3,Goncalves Marcus Vinicius Magno4,Jovem Cassio Lemos5,Matta Andre Palma da Cunha6,Oliveira Joao Filipe7,Siquinelli Fabio7,Tauil Carlos Bernardo5,Troiani Guilherme Navarro1,Wille Paulo Roberto8

Affiliation:

1. Universidade Metropolitana de Santos, Brasil

2. Hospital Sirio-Libanes, Brasil

3. Hospital Beneficência Portuguesa, Brasil

4. Centro Hospitalar Unimed, Brasil

5. Hospital de Base do Distrito Federal, Brasil

6. Universidade Federal Fluminense, Brasil

7. Universidade Regional de Blumenau, Brasil

8. IdHera, Brasil

Abstract

ABSTRACT Superficial siderosis (SS) of the central nervous system (CNS) is a rare and possibly underdiagnosed disorder resulting from chronic or intermittent bleeding into the subarachnoid space, leading to deposition of blood products in the subpial layers of the meninges. Magnetic resonance imaging (MRI) shows a characteristic curvilinear pattern of hypointensity on its blood-sensitive sequences. Methods Series of cases collected from Brazilian centers. Results We studied 13 cases of patients presenting with progressive histories of neurological dysfunction caused by SS-CNS. The most frequent clinical findings in these patients were progressive gait ataxia, hearing loss, hyperreflexia and cognitive dysfunction. The diagnoses of SS-CNS were made seven months to 30 years after the disease onset. Conclusion SS-CNS is a rare disease that may remain undiagnosed for long periods. Awareness of this condition is essential for the clinician.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3