A histomorphometric study of unmyelinated fibers of the fibular nerve in Wistar rats

Author:

Tognon-Miguel Vânia1,Nascimento-Elias Adriana Helena do2,Schiavoni Maria Cristina Lopes1,Barreira Amilton Antunes1

Affiliation:

1. Universidade de São Paulo, Brasil

2. Universidade de São Paulo, Brasil; Universidade de São Paulo, Brasil

Abstract

ABSTRACT There are few histomorphometric studies on the unmyelinated fibers of the fibular nerve in rats, and the number of experimental studies using this nerve has been increasing in the last years. Sixty-two percent of the endoneurial area from 10 fibular nerves of adult Wistar rats was scanned by electron microscopy, and digitized. The total number of unmyelinated axons (1.882 ± 271) was significantly lesser, and their axon diameters (0.2 µm to 2.8 µm) significantly higher than that determined in previous studies. The histogram peaked at 1 µm. The differences could be due to the nerve sampled area, the number and the age of the animals evaluated, and the laboratory techniques used. This study brings new and referential data to be used in experimental investigations involving histomorphometric evaluation of the rat fibular nerve.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

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