Middle cerebral artery aneurysms: aneurysm angiographic morphology and its relation to pre-operative and intra-operative rupture

Author:

Estevão Iracema Araújo1,Camporeze Bruno1,Araujo Jr Antonio Santos de2,Nery Breno3,Antunes Ápio Claudio Martins4,Smith Timothy R.5,Aguiar Paulo Henrique Pires de6

Affiliation:

1. Universidade São Francisco, Brasil

2. Araujo e Fazzito Neurocirurgião e Neurologistas Associados, Brasil

3. Hospital Santa Paula, Brasil

4. Hospital de Clínicas de Porto Alegre, Brasil; Universidade Federal do Rio Grande do Sul, Brasil

5. Harvard University, USA

6. Hospital Santa Paula, Brasil; Universidade Federal do Rio Grande do Sul, Brasil; Pontifícia Universidade Católica de São Paulo, Brasil

Abstract

ABSTRACT Objective Correlate the middle cerebral artery bifurcation aneurysm morphology with the pre-operative and intra-operative risk of rupture. Methods Forty patients with 46 middle cerebral artery bifurcation aneurysms were treated microsurgically by the same surgeon. Aneurysms were classified according to shape and the Fisher test was applied to analyze the effect of morphology on the pre-operative and intra-operative rupture. Results Pre-operative and intra-operative ruptures were observed in 8/46 patients (17.4%) and 14/46 patients (30.4%) respectively. Thirty-two cases (69.6%) had no symptoms postoperatively, modified Rankin score (MRS) of 0; 6.5% had MRS of 1 (no significant disability); 13% had MRS of 2 (slight disability); 4.3% had moderately severe disability (MRS of 4); and there were 3 deaths (6.5%) post-operatively. The morphology was not directly related to the rupture rate. Conclusion In general, ruptures are not affected by the morphology or the studied variables. Larger series are needed to validate these outcomes.

Publisher

FapUNIFESP (SciELO)

Subject

Neurology,Neurology (clinical)

Reference28 articles.

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3. Follow-up of intracranial aneurysms in autosomal-dominant polycystic kidney disease;Gibbs GF;Kidney Int,2004

4. Clinical and genetic features of Ehlers-Danlos syndrome type IV, the vascular type;Pepin M;N Engl J Med,2000

5. Familial intracranial aneurysms;Ronkainen A;Lancet,1997

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