Affiliation:
1. Mackenzie Presbyterian University
2. São Francisco University
3. Sorocaba University
4. University of São Paulo
Abstract
The aim of this paper was to emphasize the importance of prodrug design to therapy, by examining examples available on the Brazilian pharmaceutical market. The principles of prodrug design are briefly discussed herein. Examples of prodrugs from many important therapeutic classes are shown and their advantages relative to the drugs they are derived from are also discussed. Considering the importance of these therapeutic classes, from both therapy and economic standpoints, prodrug design is a very valuable aspect in the research of new drugs and for the pharmaceutical industry as a whole.
Subject
General Pharmacology, Toxicology and Pharmaceutics
Cited by
11 articles.
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