Spectroscopic and thermal characterization of alternative model biomembranes from shed skins of Bothrops jararaca and Spilotis pullatus

Author:

Baby André Rolim1,Lacerda Áurea Cristina Lemos1,Sarruf Fernanda Daud1,Pinto Claudinéia Aparecida Sales de Oliveira1,Consiglieri Vladi Olga1,Serra Cristina Helena dos Reis1,Velasco Maria Valéria Robles1,Kawano Yoshio1,Kaneko Telma Mary1

Affiliation:

1. University of São Paulo

Abstract

Recently, there has been an interest in the use of shed snake skin as alternative model biomembrane for human stratum corneum. This research work presented as objective the qualitative characterization of alternative model biomembranes from Bothrops jararaca and Spilotis pullatus by FT-Raman, PAS-FTIR and DSC. The employed biophysical techniques permitted the characterization of the biomembranes from shed snake skin of B. jararaca and S. pullatus by the identification of vibrational frequencies and endothermic transitions that are similar to those of the human stratum corneum.

Publisher

FapUNIFESP (SciELO)

Subject

General Pharmacology, Toxicology and Pharmaceutics

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