Affiliation:
1. Universidade de São Paulo, Brazil
Abstract
Platforms able to storage, release or scavenge NO in a controlled and specific manner is interesting for biological applications. Among the possible matrices for these purposes, dendrimers are excellent candidates for that. These molecules have been used as drug delivery systems and exhibit interesting properties, like the possibility to perform chemical modifications on dendrimers surface, the capacity of storage high concentrations of compounds of interest in the same molecule and the ability to improve the solubility and the biocompatibility of the compounds bonded to it. This review emphasizes the recent progress in the development and in the biological applications of different NO-releasing dendrimers and the nitric oxide release pathways in these compounds.
Subject
General Pharmacology, Toxicology and Pharmaceutics
Reference101 articles.
1. Toward photoswitchable dendritic hosts: Interaction between azobenzene-functionalized dendrimers and eosin;ARCHUT A.;J. Am. Chem. Soc.,1998
2. Dendrimers designed for functions: from physical, photophysical, and supramolecular properties to applications in sensing, catalysis, molecular electronics, photonics, and nanomedicine;ASTRUC D.;Chem. Rev.,2010
3. Nitric oxide deficiency in chronic kidney disease;BAYLIS C.;Am. J. Physiol. Renal. Physiol.,2008
4. Protein disulfide-isomerase mediates delivery of nitric oxide redox derivatives into platelets;BELL S.E.;Biochem. J.,2007
5. Functionalization of PAMAM dendrimers with [RuIII(edta)(H2O)]-;BENINI P.G.Z.;Nitric Oxide,2008
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