American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice-Reference-Cited by-同舟云学术

American trypanosomiasis (Chagas' disease) in conventional and germfree rats and mice

Published:1987-10 Issue:5 Volume:29 Page:284-288
ISSN:0036-4665
Container-title:Revista do Instituto de Medicina Tropical de São Paulo
language:
Short-container-title:Rev. Inst. Med. trop. S. Paulo

Author:

Silva Marcelo E.¹,Evangelista Elizio A.²,Nicoli Jacques R.²,Bambirra Eduardo A.³,Vieira Enio C.³

Affiliation:

1. Universidade Federal de Ouro Preto, Brasil

2. Universidade Federal de Minas Gerais, Brasil

3. UFMG

Abstract

Germfree (GF) and conventional (CV) CFW (LOB) mice and Wistar and Sprague-Dawley rats were infected with Trypanosoma cruzi. The disease was more severe in the GF than in the CV animals as revealed by: (1) an earlier and more intense parasitemia; (2) a more precocious mortality; (3) a twice enlarged spleen: (4) a more intense cell and tissue parasitism; (5) visceral signs of cardiac failure.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

Link

http://www.scielo.br/pdf/rimtsp/v29n5/04.pdf

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