The effect of chronic ingestion of ethanol on modulation of granulomatous inflammation in experimental schistosomiasis in mice

Author:

Castro L.P.F.1,Bambirra E.A.1,Coelho P.M.Z.2,Silva M.E.3

Affiliation:

1. UFMG

2. UFMG; UFMG

3. Universidade Federal de Ouro Preto

Abstract

We studied the role of ethanol on the modulation of liver granulomata around Schistosoma mansoni eggs in mice. Albino mice, receiving 7% ethanol as the sole drinking liquid, at 60 and 90 days post-infection, presented smaller granulomata than controls did, when sacrificed at 120 days post-infection. No differences in diameters could be observed, when ethanol was given 4 months before up to 120 days after infection. The results suggested that modulation of schistosome granulomata by ethanol ingestion varies with time and duration of drug consumption.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

Reference13 articles.

1. Mild prolonged schistosomiasis in mice: alterations in host response with time and the development of portal fibrosis;ANDRADE Z.A.;Trans. roy. Soc. trop. Med. Hyg.,1964

2. Immunoregulation of granuloma formation in murine schistosomiasis mansoni;BOROS D.L.;Ann. N.Y. Acad. Sci.,1986

3. Alcohol use among adolescents in S5o Paulo, Brazil;CARLINI B.H.;Drug Alcohol Depend.,1986

4. Efeito da ingestão crônica de etanol na modulação da resposta inflamatória granulomatosa esquistossoinótica no fígado de camundongos;CASTRO L.P.F.,1991

5. Cell-mediated immune responses associated with short-term alcohol intake;DEHNE N.E.;Alcoholism,1989

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3