ANTIFUNGAL ACTIVITY OF SILVER NANOPARTICLES OBTAINED BY GREEN SYNTHESIS

Author:

MALLMANN Eduardo José J.1,CUNHA Francisco Afrânio2,CASTRO Bruno N.M.F.1,MACIEL Auberson Martins2,MENEZES Everardo Albuquerque1,FECHINE Pierre Basílio Almeida1

Affiliation:

1. Universidade Federal do Ceará, Brazil

2. Universidade Federal do Ceará, Brazil; Universidade Federal do Ceará, Brazil

Abstract

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

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