Rhinoscleroma: eight Peruvian cases

Author:

Maguiña Ciro1,Cortez-Escalante Juan2,Osores-Plenge Fernando1,Centeno Jorge1,Guerra Humberto1,Montoya Manuel1,Cok Jaime3,Castro Cleudson2

Affiliation:

1. Instituto de Medicina Tropical Alexander von Humboldt, Peru

2. Universidade de Brasília, Brasil

3. Hospital Cayetano Heredia, Peru

Abstract

Rhinoscleroma is a rare infection in developed countries; although, it is reported with some frequency in poorer regions such as Central Africa, Central and South America, Eastern and Central Europe, Middle East, India and Indonesia. Nowadays, rhinoscleroma may be erroneously diagnosed as mucocutaneos leishmaniasis, leprosy, paracoccidioidomycosis, rhinosporidiasis, late syphilis, neoplasic diseases or other upper airway diseases. From 1996 to 2003, we diagnosed rhinoscleroma in eight patients attended in the Dermatologic and Transmitted Diseases service of "Cayetano Heredia" National Hospital, in Lima, Peru. The patients presented airway structural alterations producing nasopharyngeal, oropharyngeal and, in one patient, laryngeal stenosis. Biopsy samples revealed large vacuolated macrophages (Mikulicz cells) in all patients. Ciprofloxacin 500 mg bid for four to 12 weeks was used in seven patients and oxytetracycline 500 mg qid for six weeks in one patient. After follow-up for six to 12 months the patients did not show active infection or relapse, however, all of them presented some degree of upper airway stenosis. These cases are reported because of the difficulty diagnosing the disease and the success of antibiotic treatment.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

Reference38 articles.

1. Otoscleroma;ABOU-BIEH A.;J. Laryngol. Otol.,1975

2. Scleroma of the upper respiratory passages: a CT study;ABOU-SEIF S.G.;J. Laryngol. Otol.,1991

3. Iron-deficiency in atrophic rhinitis & scleroma;AKHNOUKH S.;Indian J. med. Res.,1987

4. Laryngotracheal manifestations of rhinoscleroma;AMOILS C.P.;Ann. Otol. Rhinol. Laryngol.,1996

5. Rhinoscleroma: a growing concern in the United States? Mayo Clinic experience;ANDRACA R.;Mayo Clin. Proc.,1993

Cited by 22 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3